blog

Managing MTHFR is complex as every individual is unique. The type and number of MTHFR mutations greatly affects the approach to care and the outcome of care. Treatment should optimize the production of methyl groups while decreasing the overall depletion.

Genetics cannot be changed, but how genes behave can be altered with a comprehensive diet and lifestyle approach designed to support proper and efficient methylation. Supplementation is also a factor to consider, but is again, complex. It is not a one-size-fits-all approach.

Here is an overview of common approaches to supplementation for MTHFR:

Dr. Ben Lynch’s Approach — Begin with low doses of B12 for several days, then add MTHF folate at a ratio that is ½ the amount...

Read more

An estimated 50 percent of the population has some type of MTHFR mutation that can cause health conditions ranging from cardiovascular problems, to neurologic disorders, and systemic conditions such as nausea, hair loss, immune dysfunction, and some cancers. How do you know if you carry on of the more than 40 known variants of the MTHFR gene?

Genetic testing is required to identify or rule out an MTHFR mutation. Genetic testing analyzes at the two copies of DNA strand that encodes the MTHFR genes. Of the two copies of this gene, one is essentially an “extra” copy that serves as a backup should the other copy fail to function properly. While an error on one copy of this DNA results in decreased methyl group production, it is w...

Read more

The MTHFR gene mutation is a common genetic variant that can cause a number of health conditions, including birth defects, neurological disorders, and some cancers. MTHFR adds a methyl group to folic acid, making it usable by the body.

An estimated 50 percent of the population has some type of MTHFR mutation (at least 40 variants of the gene have been identified through genetic testing). Are you among the 50 percent?

A genetic mutation, combined with the influence of methylation and environmental elements can cause a number of symptoms, often varying from one person to the next. Number and type of mutations and quality of one’s diet can affect symptoms—and symptoms can affect every system in the body.

There are essentially th...

Read more

Methylenetetrahydrofolate Reductase Gene Mutation–that’s a mouth full! Genetics determine more than the color of your eyes. As we learned in the previous series, genetics can affect your health in a number of ways. The MTHFR gene mutation (a fairly common genetic variant) can be a factor in a myriad of medical conditions. Through genetic testing, more than 40 variants of the gene that encodes the MTHFR enzyme have been identified.

What is MTHFR and what does it do?

MTHFR is an enzyme encoded by the MTHFR gene. The enzyme adds a methyl group to folic acid, making it usable by the body. A mutation of the MTHFR gene may be linked to serious health conditions, such as birth defects, neurological disorders, and some cancers.

It is...

Read more